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Umhlaza wodakada ngumhlaza oqala kudakada.I-pancreas ivelisa i-enzymes kunye namahomoni afunekayo ukuququzelela ukugaya kunye nokulawula amanqanaba eswekile yegazi.
Iimpawu ezithile zebhayoloji, ezibizwa ngokuba zii-tumor markers, zinokufumaneka kwigazi lezigulana ezinomhlaza wepancreatic.Aba bamakishi abanakunceda kuphela oogqirha baxilonga umhlaza we-pancreatic, kodwa babonise ukuba unyango lusebenza.
Kweli nqaku, sivavanya iimpawu eziqhelekileyo zomhlaza we-pancreatic, ukusetyenziswa kwazo, kunye nokuchaneka.Siphinde sajonga ezinye iindlela zokuxilonga umhlaza wepancreatic.
Iimpawu ze-tumor ziveliswa ziiseli zomhlaza okanye ziveliswe ngumzimba wakho ukuphendula umhlaza.Iimpawu ze-tumor zidla ngokuba ziiprotheyini, kodwa zinokuba zezinye izinto okanye utshintsho lwemfuzo.
Ezi proteni zimbini zinokubakho kumanqanaba aphezulu egazi kumhlaza wepancreatic.Zingasetyenziselwa ukuxilonga umhlaza we-pancreatic kunye nokuqonda iziphumo zonyango lomhlaza we-pancreatic.
Iisampulu zegazi ezithathwe kumthambo ongalweni zisetyenziselwa ukulinganisa amanqanaba e-CA19-9 kunye ne-CEA.Le theyibhile ingezantsi ibonisa uluhlu oluqhelekileyo noluphezulu kuzo zombini iziphawuli zethumba.
Ngokomzekelo, ezinye izigulana ezinomhlaza we-pancreatic zisenokungabi nawo amanqanaba aphezulu e-CA19-9 okanye i-CEA.Uphononongo oluninzi lubonise ukuba ulwahlulo oluthile lwemfuzo luchaphazela amanqanaba ophawu lomhlaza wepancreatic.
Uphononongo luka-2018 luthelekisa ukuba luncedo kokulinganisa i-CA19-9 kunye ne-CEA ekufumaneni umhlaza we-pancreatic.Ngokubanzi, i-CA19-9 yayinovakalelo ngakumbi kune-CEA yokuchongwa komhlaza wepancreatic.
Nangona kunjalo, olunye uphononongo kwi-2017 lufumene ukuba i-CEA ihlala ibalulekile ekuxilongweni komhlaza we-pancreatic xa isetyenziswe ngokudibanisa ne-CA19-9.Ngapha koko, kolu phononongo, amanqanaba aphezulu e-CEA anxulunyaniswa kakhulu ne-prognosis embi.
Uphononongo luka-2019 malunga nokusetyenziswa kweempawu zethumba ukuqikelela impendulo kunyango lomhlaza wepancreatic lugqibe kwelokuba idatha yangoku ayonelanga kwaye uphando oluninzi luyafuneka.Uphononongo lweempawu ze-tumor ezisetyenziselwa ukufumanisa ukuphindaphinda komhlaza we-pancreatic ngo-2018 zixhasa ezi ngcamango.
Ukongeza kuvavanyo lweempawu zethumba, oogqirha banokusebenzisa ezinye iimvavanyo ezininzi ukufumanisa umhlaza wepancreatic.Oku kuquka:
Uvavanyo lomfanekiso lunceda ugqirha wakho ukuba ajonge ngaphakathi emzimbeni wakho ukuze afumane iindawo ezinokuba ngumhlaza.Banokusebenzisa iimvavanyo ezahlukeneyo zokujonga umhlaza wepancreatic, kubandakanya:
Ukongeza kuvavanyo lwegazi lweempawu zethumba, oogqirha banokuyalela ezinye iimvavanyo zegazi ukuba bayakrokrela umhlaza wepancreatic.Oku kuquka:
I-biopsy ibandakanya ukususa isampulu encinci yethishu kwindawo yethumba.Isampulu ihlalutywa elabhoratri ukufumanisa ukuba iqulethe iiseli zomhlaza.
Ukuba umhlaza ufunyenwe, olunye uvavanyo lunokwenziwa kwisampulu ye-biopsy ukujonga iimpawu ezithile zebhayoloji okanye utshintsho lwemfuzo.Ubukho okanye ukungabikho kwezi zinto kunokunceda ukumisela ukuba luhlobo luni lonyango olucetyiswayo.
I-American Gastroenterological Association (AGA) icebisa ukuba abantu abasemngciphekweni owongeziweyo ngenxa yembali yentsapho yomhlaza wepancreatic okanye isifo sofuzo esizuzwe njengelifa bacinge ngokuvavanyelwa umhlaza wepancreatic.
Ubudala obuqala ngalo ukuhlolwa kuxhomekeke kwiimeko zomntu ngamnye, njengoko kucetyiswa yi-AGA.Ngokomzekelo, inokuqala kwiminyaka engama-35 kubantu abane-Peutz-Jeghers syndrome, okanye kwiminyaka engama-50 kubantu abanembali yentsapho yomhlaza we-pancreatic.
Ukuhlolwa komhlaza wePancreatic kubandakanya ukusetyenziswa kweMRI kunye ne-endoscopic ultrasound.Uvavanyo lwemfuzo lunokucetyiswa.
Uvavanyo lwenziwa rhoqo emva kweenyanga ezili-12.Nangona kunjalo, ukuba oogqirha bafumana iindawo ezikrokrelayo kwi-pancreas okanye ezijikeleze i-pancreas, banokulenza libe lifutshane eli xeshana, ukwenza ukuhlolwa rhoqo.
Isigaba sokuqala somhlaza we-pancreatic ngokuqhelekileyo awubangeli zimpawu.Kungenxa yoko le nto iintlobo ezininzi zomhlaza we-pancreatic zingabonwa kude kube semva kwexesha.Ukuba kukho, iimpawu zomhlaza we-pancreatic zingabandakanya:
Nangona ezinye iimvavanyo zinceda kakhulu kwinkqubo yokuxilonga, ekuphela kwendlela ethembekileyo yokuxilonga umhlaza we-pancreatic kukuhlalutya isampuli yezicubu ze-biopsy.Oku kungenxa yokuba iisampulu ezivela kwindawo echaphazelekayo zinokuvavanywa ngokuthe ngqo kwiiseli zomhlaza.
Ngokutsho kwe-American Cancer Society, umhlaza we-pancreatic uthatha malunga neepesenti ezi-3 zazo zonke i-cancer e-United States.Umngcipheko wokuphila ubomi obuqhelekileyo wokuba nomhlaza we-pancreatic emntwini umalunga ne-1 kuma-64.
Umhlaza wePancreatic kunzima ukuwubona kwangethuba.Abantu abaninzi abafumani zimpawu de umhlaza uqhubele phambili.Kwakhona, ngenxa yokuba i-pancreas ibekwe nzulu emzimbeni, amathumba amancinci kunzima ukuwabona ngemifanekiso.
Amathuba okufunyanwa kwangoko komhlaza wepancreatic aphucukile ngokwenene.Ngokutsho kweZiko leSizwe loMhlaza, izinga leminyaka emi-5 lokusinda kumhlaza wepancreatic kuphela yi-43.9%.Oku kuthelekiswa ne-14.7% kunye ne-3.1% yokusasazwa kwengingqi kunye nokude, ngokulandelanayo.
Iimpawu ze-tumor zi-biomarkers eziveliswa ziiseli zomhlaza okanye umzimba ukuphendula umhlaza.Iimpawu ezisetyenziswa ngokuqhelekileyo zomhlaza we-pancreatic yi-CA19-9 kunye ne-CEA.
Ngelixa iziphumo zovavanyo lwegazi kwezi biomarkers zinokubonelela ngolwazi oluluncedo koogqirha, uvavanyo olongezelelweyo luhlala lufuneka.Oku kunokubandakanya uvavanyo lwemifanekiso, uvavanyo lwegazi olongezelelweyo, kunye ne-biopsy.
Ukuhlolwa komhlaza we-pancreatic kunokwenziwa kubantu abanembali yentsapho yomhlaza we-pancreatic okanye ezinye ii-syndromes zofuzo.Ukuba kukho naziphi na ezi zingentla zisebenza kuwe, thetha nogqirha wakho malunga nokuba ungaqala njani kwaye nini ukuvavanya umhlaza wepancreatic.
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Oogqirha basebenzisa iintlobo ezimbini ze-ultrasound ukufumanisa kunye nokuxilongwa komhlaza we-pancreatic: i-ultrasound yesisu kunye ne-endoscopic ultrasound.Funda ngakumbi nge…
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Funda malunga nezona ndlela ziqhelekileyo zotyando zomhlaza we-pancreatic, kubandakanya ixesha lokuzisebenzisa, utyando, ukuchacha, kunye ne-prognosis.
Uvavanyo lwegazi luyinxalenye ebalulekileyo yokufumanisa umhlaza we-pancreatic.Nangona kunjalo, ezi mvavanyo zodwa azanelanga ukuqinisekisa ukuxilongwa komhlaza we-pancreatic ...
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