Iimveliso

Umlinganiselo okhawulezileyo we-BNP ukufumanisa ukuba isigulana esibonakalisa ukuphefumla kancinci sinokuba sinengxaki yokungaphumeleli kwentliziyo.

I-BNP ifihliwe yi-cardiomyocytes kwaye inokuthintela ukwanda kweeseli ze-vascular smooth muscle kunye ne-fibroblasts, idlala indima ebalulekileyo ekuhlaziyweni kwe-vascular kunye nokulawulwa kwengcinezelo yegazi.Kwimeko ye-hypervolemia okanye ezinye iimeko ezibangela ukunwebeka kwe-ventricular, umzimba udibanisa i-BNP kwaye uyifihle egazini ukuze ulawule ukulinganisela kwamanzi omzimba kunye ne-electrolyte ngokusebenzisana ne-renin angiotensin aldosterone system (RAAS).Kwizifo zentliziyo ezifana nokungaphumeleli kwentliziyo, uxinzelelo lwegazi, i-acute myocardial infarction, i-myocardial hypertrophy kunye ne-cardiomyopathy, i-B-type brain natriuretic peptide gene expression, i-synthesis kunye ne-secretion yanda kakhulu.Ke ngoko, i-peptide yengqondo ye-natriuretic ingasetyenziswa kuxilongo oluncedisayo lokungaphumeleli kwentliziyo.